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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

这位无懈可击的歌手用吉他和铜管乐器合成的节拍和强节奏的音乐效果展现了更为广阔的情感和音乐世界。它会使你回想起艺术摇滚乐教母凯特·布什(你可以去听一下《Green Light》(《绿灯》)这首歌)。
['?ltimit]

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

这句话是唯一来自现实世界而不是网络的。一位政府官员在回答《焦点访谈》记者“天津市每年要偿还公路建设的贷款量有多大”的问题时,回答到“这事儿不能说太细”,网民们觉得这句话很有意思,于是流传甚广。
"You can no longer have some countries go first and others come in later, because there is no more time," said Glen P. Peters, a scientist at the Center for International Climate and Environmental Research in Oslo, who helped compile the new numbers. "It needs to be all hands on deck now."

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

单词illegal 联想记忆:

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

Blake Griffin's high school appearance isn't that far off from how he looks today. Just add some hair and some size to his biceps, and you've got Blake Griffin today.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Chinese exports rose at more than twice the rate expected in November, boosting the country’s trade surplus.
The Brexit trade uncertainty
或许不会是一个超新星,但是会有好球员快速地把他们拉回正轨,比我们之前讨论的其他队伍都要快。打完这个赛季,还完之前的债,然后就可以潇洒甩头,大步向前了。
tox毒,ic-有毒的

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

But closing the deal on RCEP less than a year after Donald Trump pulled the US out of the TPP would be a big win for Beijing.
The joint programme delivered by IQS of Spain, Fu Jen Catholic University in Taiwan and the University of San Francisco saw the biggest rise. Its Master in Global Entrepreneurship Management jumps 34 places to 43rd, making up for a drop of 19 places the previous year. The only programme to be delivered on three continents, it is ranked top for international course experience.
我预计,将有更多公司培养懂得如何管理网络的领导人——不只是传统的内部员工网,还包括联系更松散的供应商和承包商网络,通过互联网和社交媒体进行远程管理。
adj. 深思的,体贴的

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

单词affection 联想记忆:

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

n. 免疫,免疫性,免除

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

达奇斯说:在这一年中,卡夫支持转基因食物,这个决定使得这个品牌成为了2012年的输家。
单词transport 联想记忆:

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

4. Adidas. Brand love: 35% / Rank 25
Meanwhile, he was being ferried around the globe to tech conferences, getting introduced to other potential investors. D'Aloisio made a remarkable impression on everyone he crossed paths with. 'He has an eerie maturity,' says Andrew Halls, headmaster of the King's College School in Wimbledon, which D'Aloisio has attended since he was 11. 'He has an extraordinary articulateness in the face of situations that, for me, even as a 54-year-old, might be terrifying.'

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

n. 校订,修正,修订本,复习
《内布拉斯加》(Nebraska)以明快的黑白片形式拍摄,通过一次穿越蒙大拿和内布拉斯加的旅行揭示了由布鲁斯?邓恩(Bruce Dern)扮演的易怒老头伍迪?格兰特(Woody Grant)的内心世界。(这部电影的摄影师芬顿?帕帕迈可(Phedon Papamichael)也参演了影片。)编剧鲍勃?尼尔森(Bob Nelson)炮制了优秀的剧本,而亚历山大?佩恩(Alexander Payne)的导演工作也无懈可击。这部影片讲述的是伍迪和儿子威尔(Will)关系不佳、最终和解的过程;扮演儿子的威尔?福特(Will Forte)极度平和的表演征服了观众。这里是很少在银幕上得到刻画的美国心脏地带,带着幽默和几乎可以感知的深情。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

Yes. Mr Modi’s overnight ban on using high-value bank notes was a big shock, and seriously disrupted the economy. But it delivered rich political rewards, bolstering the premier’s image as a decisive leader willing to take tough action against corruption. With the next general elections due in 2019, Mr Modi will be tempted to deliver one more big bang to dazzle voters. Watch out for dramatic action against wealthy individuals holding properties in others’ names to hide their ownership.
单词virtue 联想记忆:
Recipient: Their Royal Highnesses The Duke and Duchess of Cambridge (joint winners)
Hilcorp Energy

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Online peer-to-peer lending platforms have expanded rapidly in China, along with fraud cases.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

An industry insider said the survey indicated that China was in the process of an industrial upgrade and a high value-added service sector was on the rise. This is leading to a thriving Internet industry, which needs science and engineering professionals, and a booming finance industry, which requires finance and economics professionals.
沃伦·比蒂和费·唐纳薇在宣布奥斯卡最佳影片奖时,因为错拿了评奖结果卡片,误将得奖影片念成了《爱乐之城》,而不是《月光男孩》。事后,负责处理奥斯卡奖项结果的会计公司发了一份公开道歉声明。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

鉴于FIFA世界杯将于2018年在俄罗斯举办,届时的旅游成本会大大提高,所以选择在2017年去可谓是明智之举。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

6. Gene therapy comes good.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

但是,贝克?麦坚时律所并购业务主席迈克尔?德佛朗哥(Michael DeFranco)对中国企业在发达经济体投资表示赞赏。
蕾哈娜在榜单上排名第二,获得亚军,《男人装》表示:在这12个月以来,她真是无处不在,但是我们依然没有对她审美疲劳。
与此同时,大学毕业生选择继续深造的意向也降低了,这让今年选择就业的人数比例达到了75.6%,而去年这一数据为71.2%。
The S&P 500’s total return of 14% this year was 40% higher than its 25-year average annual gain. Wall Street’s chief strategists spent much of the last 12 months revising their targets higher from behind. The index printed over 50 all-time record closes, with nearly all investment management professionals racing to at least pull even. A few characteristics made the U.S. stock market particularly difficult to keep up with this year.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

Of course, these same new forces may also trigger a backlash and a reversion to old command-and-control ways of leading. The politicians who dominate the world stage are, depressingly, mostly cut from the old cloth, and the leadership challenges they face, from Brexit to North Korea, are particularly complex.
Talking to Town & Country, Industry Kitchen Executive Chef Braulio Bunay said he was inspired to create the pizza by the city's Financial District, which he described as 'the epitome of decadence'.
我们完全有能力扩大就业,不会也不允许出现大规模群体性失业。
2. Audiologist
昨日,中国四大国有银行中的两家——中国工商银行(ICBC)和中国银行(BoC)——均报告称,2015年全年净利润增长低于2%。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

May the glow of New Year candle fill your heart with peace and pleasure and make your New Year bright.
这一问题也打击了中国在WTO框架内获得市场经济地位的努力。中国声称,在其加入WTO满15周年的今年12月,应当自动获得市场经济地位。如果中国获得了该地位,那么这可能影响美国等国对中国发起反倾销案的能力,因为这将使他们不能用替代国的价格进行比价。

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

Trium在三个指标上名列第一:攻读课程前学员的工作经历、实现的目标,以及国际课程经历。该课程学员在毕业3年后的平均薪资排名第二(30.7003万美元),仅次于Kellogg/HKUST联合推出的课程。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

6、《招魂2:恩菲德的骚灵》

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

The fruit is placed into the mold when it's young and undeveloped.
5、Poor e-mail communication
The North has already warned that Park will "pay for his crimes in blood" if copies of the film make it across the border.
源于:sloth(n (对工作)懒惰)slou=slow,ch吃:吃得慢-无精打采的样子

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

荷兰合作银行表示,预计大豆价格将保持强劲,目前在1蒲式耳10美元上方,同时由于需求稳定上升,预计奶制品价格明年也将上涨。
遇到别人我能很轻松地和他/她交谈
Will Emmanuel Macron secure a commitment from German chancellor Angela Merkel on a eurozone budget
这张专辑等于是一次直截了当的暗示,提醒着我们,不论什么时候,只要霉女王想要,她就能拿回自己在流行音乐界的领先地位。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

安娜上班的地方位于富人区的一家购物中心的车库,她抱怨道:“我去上班的路上要多花费一小时,但我却得不到一个现场看球的机会。“
单词amnesty 联想记忆:

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
From the themed collection: 燕郊二手房单价普降万元
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

China's Internet industry is often derided as a realm for knockoffs, especially of companies banned in China. Chinese search giant Baidu Inc. has a website that looks like Google Inc's. Tencent's flagship product, instant messaging service QQ, was launched in 1999 as OICQ and had similar functions to then-popular instant messaging service ICQ. Sina Corp.'s Weibo, a popular microblogging service, is invariably described as 'Twitter-like' in the Western media.
Johan Pettersson被授予搞笑化学奖,以表彰其揭示了瑞典小城Andersl?v居民的头发会变绿的原因,因为这里的水中含铜量太大。
这是自从2001年来第一次由一名既不是小梅瑟威、也不是泰格·伍兹的运动员,荣登收入榜第一名。
1、死侍
说到底,我预期这些新的领导人将开始从更广泛的候选人中选拔人员,并把不同背景的人任命为自己的直接下属,从而驳斥那些根据当前的失衡来外推还需数十年才能实现领导层男女平衡的悲观者。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

据中国电影监察机构日前表示,2016年中国票房总额有望超过2015年的440亿元人民币(折合68亿美元)。
这是传记类作品首次赢得该奖项,尽管格林斯潘的自传《动荡年代》(The Age of Turbulence)曾在2007年入围终选名单——一年之后爆发的金融危机,引发了对这位中央银行家遗产的强烈质疑。
Tumor Biology, a journal published by Springer Nature, announced last week that it had retracted the papers after an investigation showed the peer review process had been compromised.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

加拿大整体排名第二,幅员辽阔,位居世界第二。“生活质量”与“教育最佳国家”均居首位。
7. How to get a flat stomach

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

Robin Wigglesworth
['limitid]
2016年观影人数达到13.7亿人次,同比增长近8.9%。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
From the themed collection: 家具卖场弊端渐显 无促销不销售
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

这位无懈可击的歌手用吉他和铜管乐器合成的节拍和强节奏的音乐效果展现了更为广阔的情感和音乐世界。它会使你回想起艺术摇滚乐教母凯特·布什(你可以去听一下《Green Light》(《绿灯》)这首歌)。
税:2014年约为16866美元(约合人民币10.8万元)
However, the economists polled expect slightly higher growth rates and substantially higher inflation over 2016.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 佛山住房公积金利用率高
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

n. 硅

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

以下是其中最值得期待的10部,我们相信这10部电影都将成为票房宠儿,值得反复欣赏。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

当地教育主管部门已经撤销了郑州林伯强新思路生活培训学校的执照,并展开了备案调查。学校的网站仍然在线,网站上充满了迷彩装学生在表演训练的照片和"精彩讲座"的网站标签。
别了,唐(Don)和他完美的西服;别了,佩姬(Peggy)和她的格子裙;别了,琼(Joan)和她的珠光宝气以及紧身连衣裙。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
From the themed collection: “以房养老”保险3年只卖了90份
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

check
第九步 每天,告诉全世界“别BB了”,其实这样蛮圈粉的
6) My Pleasure: This subtle reminder reinforces a key point. You’re here to help others. You have all the time they need. And you’re happy to do it.
"Game of Thrones" was not only the most downloaded show of the TV season, but also the most downloaded show of the year. In fact, the per episode illegal downloads figure is higher than the best ratings "Game of Thrones" has ever had。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

周日,商务部长高虎城表示,今年中国网上零售额预计将达到4万亿元(约合6180亿美元),有望超过世界其他地区从而跃居首位。
The Martian was named best comedy or musical motion picture.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

“一个12岁的小男孩可不想在自己事业刚刚开始的时候就背负10万欧元的账单。”
The data highlight the growing anxieties in some sectors of industry about what they see as unfair competition from Chinese rivals.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

1977:“俄罗斯型流感”H1N1感染人类1977: "Russian flu" H1N1 Infects Humans

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

Google's brand is now worth more than 109 billion U.S. dollars, around 2 billion dollars more than Apple, making it the most lucrative in the world.
Company: BooginHead
Local educational authorities have since revoked Zhengzhou Boqiang New Idea Life Training School's license and launched an investigation into its record. Hauntingly, the school's website remains online, replete with photos of students in camouflage uniforms performing drills and attending what the site labels "wonderful lectures."
Maybe 'Melo's mini-fro is the missing key to an NBA Championship for the New York Knicks. Oh no, wait, the missing link is Jeremy Lin—but still, 'Melo's mini-fro wouldn't hurt the Knicks' title hopes.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

Among 36,000 who have reached celebrity status on the Internet, 74 percent are women and 87.8 percent are between 17 to 33 years old, while 89 percent have a college education. Followers are also getting younger and better educated, with 77.8 percent in the 17-to-33 age group and 75 percent with a higher education.
但多数白人常把民族和种族身份混为一谈。对很多白人来说,这种身份感觉像是支撑他们的世界最重要的支柱之一,而现在,它似乎受到了威胁。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

促进外贸继续回稳向好。
['s?m?ri]
But Huy Vo, a senior specialist in public relations at Hawaiian, said the short flights, which make up half the airline’s routes, aren’t all that easy to operate. “Our geographic location certainly does give us an advantage, as well as our short-haul routes, ” Vo said. “However, the short-haul routes are the hardest to keep punctual, because the hops are very short, with brief ground time between flights, so any delay is difficult to make up.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

initially
在开放课程排行榜顶端,赛德商学院(Sa?d Business School)排名上升幅度最大,跃升5位至第4名。这是这所位于牛津大学(University of Oxford)的商学院首次进入前五。赛德商学院在所有10项受学员评分影响的指标上的排名都有所提升。
坦白地说,这部电影2017年可能筹备不好,但是以防万一我们还是把它归进来。这是拉斯洛.奈迈施的第二部电影,2016年早些时候他凭借《索尔的儿子》摘得奥斯卡最佳外语片。《日落》是一部关于成长的电影,背景设定在一战前夕的布达佩斯。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

……被要求向面试官简单介绍自己,结果她没有什么可说的。
Season\'s greetings and sincere wishes for a bright and happy New Year!

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
From the themed collection: 广州二手网签均价 连续2个月下降
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

Liu Fei was also a half-brother of the Emperor Wu of Han who ruled from 141BC to 97BC.
However, in season two Friends took a big leap toward equality by featuring a gay wedding when Carol married her girlfriend Susan. Behind the scenes, executive producer Marta Kauffman said, "NBC expected thousands and thousands of phone calls and hate mail." However, after the episode aired, they received only four antagonistic letters. As it turns out, people just didn't care that much.
protocol

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

会是除巴西、德国和西班牙之外的国家捧得大力神杯吗?
9. HitTail

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
From the themed collection: 艾仕得“进军”未来汽车涂料市场
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

His eloquent defence of equality came after a year of faltering progress on gay marriage in the US and as arguments rage about the lack of diversity among the people running the Silicon Valley companies, including Apple, who shape so much of our culture.
芯片的零售价为150美元,但一次只能烤四寸的饼干。如果你用传统的烤箱,在烤箱烤一大批饼干,你也能在30分钟内烤完8到12块饼干,也更加便宜。
n. 品质,特质,才能

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

挪威曾为一只企鹅授予爵位。它现在居住在苏格兰的爱丁堡动物园,是那里的企鹅王,它叫尼尔斯·奥拉夫( Nils Olav)。它不仅是一只吉祥物,更是挪威皇家护卫队的名誉上校。2008年8月15日,国王哈拉尔五世(King Harald V)授予奥拉夫爵位,并在授予典礼上声明“奥拉夫在各方面都有资格获得骑士爵位的荣誉和尊严”。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

同时,大批与比特币相关的创业公司于2014年创建,表明比特币势头强劲。我们没有比特币新创企业的详尽名单,但几乎可以肯定的是,2014年成立的比特币新创企业的数量,高于此前任何年份。融资平台AngelList发给《财富》的数据证实了这一点。2011年,5家比特币初创公司在AngelList上登记。2012年,这个数字增加到13家;2013年跃升至193家;2014年更是暴增至566家。【但并非所有创业公司都会(立即)在AngelList上登记。】此外,正如巴里o希尔伯特在推特上所言,1月8日,比特币日交易总量创下历史新高。
2.富国银行

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

A Larger Profile
仪征博物馆的工作人员告诉每日邮报电子报,这件青铜器是在西汉(公元前206年–公元8年)贵族墓中发现的。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

很难想象《迷失》中若是没有杰克·谢帕德作主角,这部剧会变成什么样。大概只有编剧真的这样写了,我们才会知道答案吧。美国广播公司引进这部剧后,杰克·谢帕德这一角色本该在坠机事件中遇难,接着将由凯特在这部剧中担任更多的领导角色。
不过,行业、企业间的高管薪酬差距明显。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

He said game and live-broadcast apps currently hosted by Tencent don't require real-name registration, but the company is considering establishing a platform for parents to monitor their children's behavior.
The Suicide Squad is scheduled for an August 5th 2016 release.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

在第一部掌上移动设备发明之前,自拍杆已经问世。自拍杆其实是由一个日本男人上田宏在20世纪80年代发明的。上田宏是美能达相机公司的摄影师,他发明这个自拍杆,是因为他和妻子在欧洲旅行时无法自拍合照。(当时,他叫一个男孩帮他们拍照,那个男孩却拿着相机跑了。)

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

Tony Moloney, head of education and skills at National Grid, says the UK utility’s involvement is part of its broader strategy to encourage school students to study Stem subjects — science, technology, engineering and mathematics — and learn more about jobs in his sector.
卓越雇主排名:11
理想化地描述并粉饰往昔,把往昔置于想象中的玫瑰色光环中,这是人类的天性。
['si:nj?]

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

该排名衡量的是欧洲商学院研究生课程的质量和广度。商学院必须参与所有这4项排名,才有资格获得完整得分。伦敦商学院去年排名第三,为首次参与所有4项排名。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

8.Wheel Skates
purchase
It was in Giambattista Valli’s most recent autumn-winter show, full of puffed-sleeve printed tunics over matching trousers and drop-waisted schoolgirls shifts, and in MaxMara’s ode to Marilyn Monroe’s 1962 photo shoot with George Barris.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

Jack Ma, founder and executive chairman of e-commerce giant Alibaba Group topped the ranking of China's richest IT people for the third consecutive year.
Growth in the key sectors driving China’s economy softened last month, according to official gauges tracking activity at manufacturing, services and construction businesses.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

据教育部表示,这些学生90%以上都就读于英语国家,例如美国、英国和澳大利亚等,70%的人至少是在攻读学士学位。
Any decision by China’s policymakers to begin selling down the country’s huge reserves would have a large impact on markets.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
From the themed collection: 北京二手房交易开通“一网通办”
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

The captain must steer the ship. If leadership doesn’t know where a project or company is headed, how can the company know? This isn’t just about steps or deliverables, either, but a clear vision of the department or company’s future that he or she can communicate to the employees。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

“有个家伙有一天跟所有同事说这是他最后一天了,结果却没让老板和人力资源部经理知道。”
在导演阿方索?卡隆(Alfonso Cuaron)和同事们(其中包括知名电影摄影师艾曼努尔?卢贝兹基(Emmanuel Lubezki)、制片设计师安迪?尼克尔森(Andy Nicholson)和编剧霍纳斯?卡隆(Jonas Cuaron))的共同努力下,《地心引力》丰富了电影的拍摄手法。《美国电影摄影师》(American Cinematographer)杂志上个月的封面故事刊载了关于《地心引力》制作过程的文章,对电影技术感兴趣的读者可以一探究竟。读者们可以在网上阅读该杂志。不过任何看过《地心引力》的观众都已经领会到了该片的情感内涵,这部电影把观众们带进入了一个寂静危险的外太空和一个深度愉悦的内心世界。
The University of St Gallen’s domination of the Financial Times’ ranking of masters in management courses continues for another year.

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

竞争对手在网上的表现如何?谷歌的搜索广告关键词规划工具会帮助你解答这个问题。“搜索广告”这个词可能会令有些企业家望而却步,因为它似乎会要求你买广告位。但事实并非如此,只要有谷歌账号,任何人都能使用这个关键词规划工具(不过你首先必须点击Adwords的进入端口)。然后你可以使用关键词规划工具来看看在你从事的领域中,哪些关键词会吸引最多的搜索量,然后找出吸引流量的机会。
I don't know about you, but if I had a separate calendar for work, school and life, I'd be a complete mess. When everything in your life is on one calendar, in one planner, you can't double-book anything. You know, like an important test and a dinner with your boss.
《好时光》
6. “Taxi”(Jafar Panahi)

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

据《重庆晨报》报道,经调查后,荣昌警方于4月29日以危害公共安全的罪名逮捕了周某。
With an 8.5-percent increase in profits, industrial enterprises reversed the previous year's negative growth of 2.3 percent.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
From the themed collection: 新时代房企发展面临四维转型
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

审校:赵倩 来源:前十网
据中国岛主联盟发起者林东估计,目前中国至少有600名岛主。
JUSTIFIED (FX, Jan. 20) The series-long love-hate relationship between Deputy Marshal Raylan Givens (Timothy Olyphant) and his friend and nemesis Boyd Crowder (Walton Goggins) will be resolved, one way or another, in the show’s sixth and final season.

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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“Someone resigned via a video conference call.”
The infectious disease known as scarlet fever famously reached pandemic proportions in the 19th century, striking down the young and the weak across the Western world.

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